PHARMORPHIX® SOLID FORM SCIENCES
Johnson Matthey has leading capabilities in developing optimal polymorphs, salt forms, crystal morphology and controlled particles through its Pharmorphix® solid form sciences. We offer one of the broadest and most reliable services to ensure effective identification, development and manufacture of your drug candidates and commercial products.
Our solid form services include:
Polymorph Screening
- Reduced risk of failure during development
- Meeting regulatory requirements
- Strengthened intellectual property
Salt Screening
- Effective development of drug candidates
- Improved bioavailability
- Enhanced physiochemical properties
Co-Crystal Development
- Unique API intellectual property protection
- Increased formulation stability
- Enhanced physiochemical properties
Amorphous Dispersions
- Increased solubility and bioavailability
- Stabilised amorphous forms
- Controlled particle size distribution
Crystallography
- Dual source X-ray
- Assignment of absolute stereochemistry
- Structure determination from the smallest of crystals
Physical and Chemical Analysis
- Assess the performance of novel crystalline forms
- Design-appropriate salt and co-crystal screens
- Investigation of alternative drug delivery routes
Chiral Separations
- Optimised enantiomeric excess of chiral products
- Rapid access to single enantiomers
- Enrichment of low ee materials
Crystallisation Development
- Maximised processes yields
- Reliable crystalline form and morphology
- Controlled particle size distribution
For more information download our Solid State Services Flyer