Johnson Matthey offers a range of advanced separations technologies to meet your product purification needs for economic, efficient or scalable processing. We develop strategies using our range of tools for separations, including Supercritical Fluid Chromatography (SFC) and Preparative HPLC.

Supercritical Fluid Chromatography (SFC)

SFC is particularly useful for the purification of materials with poor solution stability. It utilises supercritical CO₂ as a replacement for traditional non-polar organic solvents. Purified fractions are separated from CO₂ in gas-liquid cyclonic separators, and the pressure is reduced to precipitate the solutes into cyclones.

Preparative HPLC

We employ preparative HPLC for the purification of multi-component mixtures when traditional purification methods are not suitable.

Our system specifications include:

• 10 - 50 cm ID columns with flow rates of up to 600 L/hr
• Custom-packing using commercially available stationary phase automated rotary evaporators and thin film evaporators (TFE) for eluent handling
• Eluant handling systems utilising automated rotary evaporators or thin film evaporators (TFE).